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As a medical device, it is FDA approved but hasnt been tested like pharmaceuticals would be to the highest level of medical evidence and scrutiny

Russell Hill, MD Medical Director Dr

As mentioned before, dietary Cu overload may accelerate liver injury in Wilson disease

We will analyse the effect of vitamin B 12 separately in the following subgroups: Vitamin B 12 status: based on cobalamin (cut-off: 150 pmol/L) based on low total homocysteine (cut-off: 10 mol/L) based on low methylmalonic acid (cut-off: 0.26 mol/L) Maternal body mass index (cut-off: 18.5) Vegetarian (yes/no) Birth weight (cut-off: 2500 g) In these subgroup analyses, the differences in the effect between the levels of the subgroups will be measured by including two-way interaction terms in multiple regression models