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Description

This design choice introduces potential bias, particularly for subjective outcomes, but it reflects the practical reality that these treatments have different injection devices and titration schedules that would make blinding extremely difficult

This research was funded by Kunming Medical University Alliance Special Project (No.202501AY070001-233), Yunnan Provincial Department of Education Scientific Research Fund (No.2024J0310), Talent cultivation Program of Fuwai Yunnan Hospital, Chinese Academy of Medical Sciences (No.2024RCTJ-QN-005, No.2025YFKT-PY-07, No.2025YFKT-ZL-10), the Yunnan Provincial Clinical Medicine Research Special Program (No.202405AJ310003)