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In addition, it is accompanied by enhanced apoptotic cell death in the lamina propria and inflammatory cell infiltration [13,14,15,16]

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They change which tissues are exposed, at what concentrations, and with what safety profile

Pachman Deirdre R, Qin R, Seisler Drew K, Smith Ellen ML et al (2015) Clinical course of oxaliplatin-induced neuropathy: results from the randomized phase III trial N08CB (Alliance)