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Neuroimaging studies have shown a reduction in hippocampal volume and abnormal prefrontal cortical activity, which strongly correlates with impairments in verbal memory and information processing speed ( 2.3.2 Psychiatric symptoms METH abuse disrupts the functionality of various brain regions, including the prefrontal cortex, nucleus accumbens, and thalamus, leading to significant psychiatric disturbances (Sekine et al., 2001)

The nuclear receptor superfamily: the second decade

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