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Glutamate-cysteine ligase (GCL) activity moderately regulates resistance to glucose deprivation The differential responses of L-cystine, L-cysteine, -GCS, and GSH upon glucose deprivation is particularly interesting because these four molecules all belong to the GSH synthesis pathway

& Thomas, M

Antivir Res 59 , 127135 (2003)

[23] have shown decreased gene expression of 26 nuclearencoded subunits of the oxidative phosphorylation chain in nondemyelinated motor cortex from MS patients, which coincided with a significant reduction in activity of NADH dehydrogenase and ubiquinolcytochrome c reductase