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Description

Nature 608 , 593602 (2022)

The assay media were collected and stored at 20 C

Three lipoxygenases, 5-lipoxygenase, 12-lipoxygenase, and 15-lipoxygenase (5-LOX, etc.), are the major LOX isoforms found in humans (Table 43-4)

Rather than focusing solely on therapeutic efficacy, this work integrates material design, localized drug delivery, and biological evaluation to explore a rectally administered strategy aimed at enhancing local radioprotection while minimizing systemic exposure