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This disruption may lead to lipid peroxidation, protein damage, cell structure destruction, and chilling injury, especially in postharvest fruits or vegetables, which is a specific symptom of cold stress (Yao et al., 2021)

Tregs contribute to the preservation of muscle integrity and mitochondrial function, playing an essential role in the bodys long-term adaptation to physical activity

Thus, CXCL-12 signaling by receptor CXCR-4 requires an intimate interaction between CAFs and tumor cells, which would result in the proliferation of tumor cells as well as acceleration of neo-angiogenesis due to the recruitment of endothelial progenitor cells (Costa et al., 2 O 2 ) (Tsai et al., 2014), can cleave and thereby inactivate SDF-1 and, in doing so, facilitate the migration of GSCs out of the niches