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doi: 10.1084/jem.20200388 52 CaoSHungYWWangYCChungYQiYOuyangCet al

Vascular aspects of multiple sclerosis

Thats the promise of Smart Brothers Dihexa, a peptide (also called PNB-0408) that crosses the blood-brain barrier, binds hepatocyte-growth-factor (HGF) with femtomolar affinity, and turbo-charges HGF/TrkB signallingseven orders of magnitude more potent than BDNF itself