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In preclinical experiments using an immunocompetent somatic mosaic genetically engineered mouse model of RMC, combination ICT accelerated tumor growth while activating myeloid-affiliated transcriptional circuits

Tissue Repair: Promotes angiogenesis and skin recovery

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Inhibition of IL-1 secretion by GSTO1 inhibitors also has exciting implications on tumour progression and tumour-immune cell crosstalk in the microenvironment