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The 40:1 ratio is commonly used in PCOS-focused formulas because it gives myo-inositol the leading role while still including D-chiro-inositol in a smaller amount

A study by Xue et al

doi: 10.3390/ijms222011248 160

The application of over-expressing or knock-out and transgenic GPx1 mouse models overwhelming in vivo evidence for the protective role of GPx1 against oxidative injury and death induced by ROS and RNS