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Researchers often investigate DSIP in laboratory settings when examining how biological systems respond to sleep signaling mechanisms and neurological peptide interactions

Despite the widespread use of CPZ as an animal model for demyelinating diseases such as multiple sclerosis (MS), the mechanism by which it induces demyelination and then allows robust remyelination is still unclear

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This neurodegeneration is accompanied by the formation of characteristic Lewy bodies, which are intracellular inclusions composed largely of aggregated and misfolded -synuclein (Balestrino and Schapria, 2020)