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Alternative splicing can also occur at the 5SS or 3SS, where using different donor or acceptor sites results in mRNAs with varied 5 or 3 ends, affecting both the mRNAs coding potential and regulatory elements 32 (Fig

Journal of Zhejian University Science B , 7 (2), 90-98

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Abnormalities in glutamate and GABA signaling have been hypothesized to underlie ASD symptoms, and may form a therapeutic target, but it is not known whether these abnormalities are recapitulated in humans with ASD, as well as in rodent models of the disorder