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Median t max appeared to be reduced in participants with renal impairment, while t 1/2 increased

Peptides are short chains of two or more amino acids (the building blocks of proteins)

Mechanistically, it has been observed that GSTP1-1 binds, in its monomeric form, both c-Jun and JNK, thus forming an heterotrimeric complex that inhibits the phosphorylation of c-Jun by JNK