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To further confirm the crosstalk between RAGE and TLR4 signaling in dAGEs-mediated allergic inflammation, we tested the expression of receptor-mediated signaling and markers related to epithelial barrier function, type-2 immunity and localized inflammation in the intestine of KO mice

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The factory starts making fewer red blood cells, and the ones it does manage to produce are oversized, poorly formed, and can't do their job properly

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