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Notably, overexpression of P53 gene is known to play a key role in reducing oxidative stress levels by, for instance, mediating enzyme activity of known ROS scavengers glutathione peroxidase (GPX) and aldehyde dehydrogenase (ALDH) [233]

After determining the administration doses, the effects of chlorophyllin and docetaxel, both individually and in combination, on the 4T1 cell cycle were assessed using flow cytometry

The top-ranking binding pose was then prepared for classical MD relaxation with the AMBER 20 77 suite using the ff14SB 78 force field for the protein and gaff2 79 for GSH and flav-3-on-4-ol

This reduction in melanin leads to lighter skin tone over time, though many wonder if its possible to reduce skin melanin permanently through such treatments