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Left untreated, bunions can worsen, leading to greater discomfort and potential mobility issues

To date, no classical ferroptosis inhibitors have entered neurodegenerative diseasespecific clinical trials but several antioxidant and radical-trapping agents (RTAs) have/are being evaluated in AD or MCI, including vitamin E (NCT00235716: 2000 IU/d of alpha tocopherol compared with placebo resulted in slower functional decline ~19% delay in clinical progression per year [58]