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doi: 10.3389/fphar.2025.1546041 Received 16 December 2024 Accepted 13 May 2025 Published 29 May 2025 Volume 16 - 2025 Edited by Massoud Ranjbar, Bu-Ali Sina University, Iran Reviewed by Yuxiang Fei, China Pharmaceutical University, China Liuqing Yang, Hangzhou Hospital of Traditional Chinese Medicine, China Updates Copyright 2025 Ju, Zhao, Li, Zhang, Xiang and Lian

This occurs mainly due to disruption of the glycocalyx in the endothelium leading to vascular leakage, coagulation and inflammation, with the heterogeneous microvascular flow and myocardial edema (59)