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ROS are a necessary defense system to combat microbial respiratory infections (Lambeth, 2004), but oxidative stress and the excessive production of ROS by numerous cells including monocytes and macrophages, neutrophils, as well as pulmonary endothelial and epithelial cells play a major role in the development of ARDS and its complications during COVID-19 infections (Meftahi et al., 2021)

It participates in neuronal repair and regeneration by up-regulating Notch1, Jagged1, and Hes1

There exists a potential association between the occurrence of CRC and specific constituents of the gut microbiota, owing to their capacity to produce a substantial quantity of genotoxic substances (Janney et al., 2020

Immune Health