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Oral melanotic macule Stock Image C067 2476 Science Photo Library Treatment of labial melanotic macules on the lip. These are benign spots that appear on the lips for no apparent reason. The causes are mostly genetic, but similar spots can appear in smokers, after Oral pigmented lesions: Clinicopathologic features and review of the literature PMC do oral melanotic macules go away Clinical Challenge: Dark Lesion on Lower Lip
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