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However, if the integrity of the BBB is compromised, it can result in ion imbalance, changes in signal molecule homeostasis, and attack by immune cells and molecules on the central nervous system, leading to neuronal dysfunction, degeneration, and various neurological diseases [47]

de Bruin, S

We refer to these multi-omics integrative approaches as physiolomics (e.g., patch-sequencing, spatial RNA-seq following in vivo imaging) or phenotomics (e.g., behavioral profiling, brain activity mapping, and clinical or pathological diagnoses)