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Both studies were conducted in accordance with Good Clinical Practice, the Declaration of Helsinki and US Food and Drug Administration/European Medicines Agency guidelines for studies in people with renal or hepatic impairment Consent to Participate/Publish All participants provided written, informed consent

It plays a role in cellular repair and regeneration, which supports healthy aging pathways

109 high-risk patients should be prioritized for screening

These reciprocal alterations in CD8 + T cell distribution suggest that therapeutic interventions targeting cellular survival mechanisms and functional restoration of both intestinal and intrahepatic CD8 + T cell populations may represent a novel therapeutic strategy for ALD management [103]