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Nature 432:396401 Ramachandran C, Portalatin G, Quirin K-W, Escalon E, Khatib Z, Melnick SJ (2015) Inhibition of AKT signaling by supercritical CO2 extract of mango ginger (Curcuma amada Roxb.) in human glioblastoma cells

Developing senolytics with high selectivity and efficacy in targeting senescent cells while minimizing off-target effects on healthy cells remains an ongoing challenge