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From homology modeling to the hit identification and drug repurposing: a structure-based approach in the discovery of novel potential anti-obesity compounds

[56], the lower Cat activity induced by various tumours has been attributed to an increase in TNF- level, which reduces hepatic Cat activity [57], [58]

reported significant reductions in inflammatory markers and oxidative stress among neonates with sepsis who received melatonin as adjunctive therapy, along with a decrease in mortality risk (El-Gendy et al., 2018)