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Variations between means were assessed by least of significant differences (LSD) at 0.05

The bone effects of amylin analogues also deserve investigation, as these drugs not only bind the amylin receptors AMY1R, AMY2R, and AMY3R, but also the calcitonin receptor, raising the possibility of direct effects on bone metabolism [10]

9,62,63,64 For instance, copper participates in myelination and interacts with synaptic proteins and neurotransmitter receptors, highlighting its significant function at synapses