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I still have spots showing up on my shoulders and chest though

The transcobalamin-bound fraction, known as holotranscobalamin or active B12, accounts for 6%-20% of bound vitamin B12

By inhibiting NNMT, 5-Amino-1MQ preserves SAM availability and reduces SAH accumulation, potentially supporting proper methylation of DNA, histones, and proteins - epigenetic modifications that regulate gene expression and cellular function