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Preclinical findings indicate that the peptide supports structural and functional preservation in a wide range of tissues, including the upper and lower gastrointestinal tract, hepatic and pancreatic tissue, skeletal muscle, ocular structures, cardiac tissue, and neural systems

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Structurally, semaglutide is a modified peptide analog of human GLP-1, designed to resist enzymatic degradation and prolong its biological half-life, allowing for once-weekly subcutaneous injection