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showed that the serum IGF-1 levels in infarcted rats were initially decreased (24 h up to 1 week) and remained unaltered during the late postinfarction period (4 to 8 weeks)

Current standard of care is based on the four out of five rule [103], which indicates that four out of five of the following criteria are enough to establish CD diagnosis: (1) typical signs and symptoms (diarrhea and malabsorption)

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