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Mol Cancer 2015

TGF-1-induced EMT activation via both Smad-dependent and MAPK signaling pathways in Cu-induced pulmonary fibrosis

Experimental studies have shown that BHB suppresses NLRP3 inflammasome activation in response to defined inflammatory stimuli (urate crystals, ATP and lipotoxic fatty acids), suggesting that this effect depends on the cellular activation state and the inflammatory context [21]