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12 Discussion To date, there are few studies demonstrating utility of topical glutathione in treating hyperpigmentation, oxidative damage, TEWL, and improving skin elasticity

Vitamin C deficiency causes oxidative damage to macromolecules (lipids, proteins) in the brain (13)

These findings, although obtained from models of oxidative stress and mitochondrial dysfunction rather than in autism models, are highly relevant because they target biological mechanism that are also characteristic of ASD (Sachdeva et al., 2022)

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