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Membrane potential dynamics of neocortical projection neurons driving target-specific signals

ENT-01 ( squalamine phosphate ) inhibits -synuclein aggregation in the gastrointestinal tract and significantly increased the number of complete spontaneous bowel movements per week after 25 days on ENT-01 treatment in a double-blind, placebo-controlled, phase 2b RCT in 150 participants with PD and constipation however at the expense of gastrointestinal AEs in up to one third of participants [166]

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Gluten withdrawal lowered NKG2D and its ligand expression in NOD and BALB/c mice, attesting to glutens impact on the co-stimulatory interplay between tolerance and immune inflammation