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However, the effects of BMI were not of sufficient magnitude to suggest that dose adjustments would be necessary [12]

A recent summary statement by Bauer et al

10.1038/srep22587 153 MustaphaM

The Tank1 binding kinase (TBK1) is a critical regulator of various forms of autophagy via the phosphorylation of autophagy receptors, promoting autophagic flux 17