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For those practicing intermittent fasting , administration at the end of the fasting window, just before breaking the fast, provides a strong lipolytic signal during an already optimized metabolic state

Vitamin B12 (cobalamin) is an essential nutrient involved in energy metabolism, nerve function, and red blood cell production

However, doctors may recommend taking B12 supplements after the age of 50 years as your ability to absorb B12 decreases with age

Vitamin B12 injections are also used by people with impaired vitamin B12 absorption or deficiency called Pernicious anaemia caused by: Inadequate dietary intake of B12 Loss of gastric parietal cells in chronic atrophic gastritis Structural damage or surgical resection of the small intestine or stomach Long-term use of acid regulating medication Alcoholism Gastric banding surgery Celiacs disease Pernicious anaemia Crohns disease Until now, injection of methyl-B12 has required a needle