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Using genetic deletion of Cth , we determined that CTH can affect macrophage function via enhanced gene and protein expression through NF-B phosphorylation and suppression of DNA methylation and maintenance of mitochondrial function through redox homeostasis

N-acetyl-cysteine (NAC) may have a therapeutic effect in OCD due to its effect on the glutamatergic system and reduction of oxidative stress

Miyoshi K, Obata K, Kondo T, Okamura H, Noguchi K (2008) Interleukin-18-mediated microglia/astrocyte interaction in the spinal cord enhances neuropathic pain processing after nerve injury