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10.1038/s41598-024-60726-y 66

The peptide has a relatively short half-life of approximately 20 minutes, meaning it clears the body quickly while stimulating growth hormone release that lasts much longer

While no further (pre)clinical interventions with NAD + modulators have been reported for this condition 263,264 , a Singaporean cohort study showed lower concentrations of circulating trigonelline, the N-methylated form of NA, in sarcopenic subjects 124