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Yes, Ipamorelin can assist with weight loss by promoting fat metabolism

Proc R Soc Ser B Biol Sci 273:579586

Safety and metabolic effects of tesamorelin, a growth hormone-releasing factor analogue, in patients with type 2 diabetes: a randomized, placebo-controlled trial

Furthermore, evidence for a central source of ghrelin remain questionable, with only very low levels being found in the hypothalamus (Hosoda et al., 2000