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The dosing protocols circulating online are extrapolations from preclinical work

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Rodent studies from the Kozlovskaya and Semenova groups at the Institute of Molecular Genetics report increased 5-hydroxyindoleacetic acid (5-HIAA) to serotonin ratios in the hypothalamus and striatum, suggesting accelerated serotonin turnover rather than raw 5-HT elevation

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