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It has been reported that extracellular lactate also increase tumor invasion and metastasis by facilitating the fibroblast expression of hyaluronan and CD44 (267)

Plant Physiol 140:613623 Smeets K, Opdenakker K, Remans T, van Sanden S, van Belleghem F, Semane B, Horemans N, Guisez Y, Vangronsveld J, Cuypers A (2009) Oxidative stress-related responses at transcriptional and enzymatic levels after exposure to Cd or Cu in a multipollution context