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Oxidative stress during viral infection: a review

To determine the effects of stimulating TCA cycle activity, we treated hepatocytes with dichloroacetate (DCA), which stimulates substrate entry into the TCA cycle by inhibiting PDKs (Constantin-Teodosiu et al., 1999, Wu et al., 2018)

84,85,161163 When MLCK1 is recruited to PAMR, it generally phosphorylates the myosin light chain (MLC), resulting in contraction of the cytoskeleton and occludin internalization