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Millipore, Merck KGaA, Darmstadt, Germany) was performed for double the highest tested concentration used in MBC testing of each substance (polyhexanide and HOCl at 25.6 mg/L, povidone-iodine and NAC at 25,600 mg/L) for all three control strains, following the ASTM International standard E 1054 2 ( 3.4 Minimal bactericidal concentration (MBC) For MBCs, stock solutions of polyhexanide, povidone-iodine, N-acetylcysteine, and hypochlorous acid were prepared and serially diluted in sterile phosphate-buffered saline (PBS) and in CAMHB, except for HOCl, which was only tested in PBS, as MIC testing had already shown a lack of efficacy for HOCl if dissolved in CAMHB

In a model of chronic allograft nephropathy (CAN), rhein significantly reduced the expression of CTGF and alleviated RF

Upon cellular delivery, the Pd-mediated cleavage of the caging group released functional Ubv2.3-aldehyde

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