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While some of these effects can be beneficial in specific contexts, they create complexity, side effects, and potential contraindications that limit the applicability of growth hormone therapy for individuals seeking primarily fat loss

Clinical trials measuring body composition found that fat mass reduction occurred without corresponding increases in lean tissue mass, confirming the absence of anabolic muscle-building effects

This process depletes cellular NAD+ and S-adenosylmethionine (SAM) two critical molecules for energy metabolism and cellular function