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Schwingel et al (11) treated BALB/c mice with OXA (10 mg/kg/week, i.p.), and reported the appearance of steatohepatitis after 6 weeks of OXA treatment

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Thiyl radicals are readily formed through homolytic cleavage of the sulfhydryl S-H bond due to low bond dissociation energies of around 87 kcal mol 1 (Dns et al., 1 or the water-soluble 2,2'-azobis[2-(2-imidazolin-2-yl)propane]-dihydrochloride (VA044) 2 radical initiator (Figure 1)

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