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Description

The applicant commented that the components of aprevo Cervical ACDF System (insertion instrument, the integrated fixation screws, and the CAM) are part of the 510(k)-cleared aprevo Cervical ACDF System and other commercially available insertion instruments and screws are not FDA authorized or compatible with the aprevo Cervical ACDF System

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In a pre-clinical setting, numerous STING agonists such as DMXAA or ADU-S100 have shown promising results by inducing a potent anti-tumor immune response either alone or in combination with other conventional cancer therapies including radio- and chemotherapy (277281)