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Description

Cholangiocarcinomacomposed of malignant duct epithelium

24 GLP-1, used for treating diabetes, is quickly broken down in the body, requiring high doses that can cause side effects like nausea

Kobayashi, T., Shiba, T., Kinoshita, A., Matsumoto, T

By inducing TGF-3 expression and activating the Smad3 pathway, it subsequently upregulates NOX4 and promotes ROS production, ultimately achieving positive reinforcement of E-P-OS network activity [Citation72]