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Severe or prolonged B12 deficiency can lead to a range of neurological manifestations, including peripheral neuropathy, which may present as pain, paraesthesia (pins and needles), or altered sensation in the extremities

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Natural Amylin 37-amino acid peptide hormone Co-secreted with insulin by pancreatic beta cells Half-life: minutes Requires multiple daily injections if used therapeutically Reduced or absent in type 1 diabetes

The Core Mechanism: The Inflammaging Loop Inflammaging: A chronic, sterile (non-bacterial) inflammation that increases with age