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Description

Mincer DL, Jialal I

Its reduced binding to IGFBPs enables prolonged activity, making it suitable for studies on protein synthesis, myoblast proliferation, fat metabolism, and PI3K/Akt pathway modulation under anabolic or repair conditions

3a), likely weakening the interaction between the catalytic core and the pHAT domains, resulting in no observed density for the pHAT domains in the cryo-EM structure of Ta OGA (Fig