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SCLA2a was able to pull down GPX4, and GPX4 pulldown was prevented by preincubation with RSL3 or SCLA2 (Extended Data Fig

Historically, attempts to halt lipid peroxidation relied on replenishing the depleted lipophilic antioxidant pool through the combined systemic administration of high-dose Coenzyme Q10 and vitamin E, or via short-chain synthetic analogs like idebenone [121,122]

Networks of WRKY transcription factors in defense signaling

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