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Moreover, the application of AI/ML as well as xAI to move beyond the limitations of black-box data-driven models is an accelerating trend, not only in biomedical fields 57,58 such as drug and cancer diagnostics but also emerging in bioprocess modeling 59

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Farooq MA, Gill RA, Ali B, Wang J, Islam F, Ali S, Zhou W (2016a) Subcellular distribution, modulation of antioxidant and stress-related genes response to arsenic in Brassica napus L

Most therapeutic interventions remain in preclinical development, with clinical translation hindered by two key barriers: The lack of validated biomarkers for patient stratification and incomplete elucidation of synergistic combination mechanisms