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Together, these findings are consistent with NETosis as an underlying mechanism for a prothrombotic state in blood leading to respiratory dysfunction

Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema

Peroxide is a long-lived reactive oxygen species with a high redox potential, which contributes to the antimicrobial effectiveness of CAP (Kondeti et al

B cells and plasma cells contribute to chronic inflammation by producing autoantibodies and cytokines that modulate the TME, while myeloid-derived suppressor cells (MDSCs) inhibit T cell activation and promote tumor tolerance through arginase-1 and ROS production [43,44,45]