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Description

Its transport is Na-and pH-dependent, however it does not require Cl ions

IDH mutations were first reported in GBM and were later found in other tumors, such as AML, cholangiocarcinoma, and chondrosarcoma (Parsons et al., 2008

Zhang Y, Swanda RV, Nie L, Liu X, Wang C, Lee H, et al

These facets of cellular metabolic dysfunction, many of which were first noted in neurons in PD, have now been shown to extend to immune cells in both the CNS and the periphery