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doi: 10.3389/fphar.2018.01120 Received 14 April 2018 Accepted 13 September 2018 Published 03 October 2018 Volume 9 - 2018 Edited by Honglin Li, East China University of Science and Technology, China Reviewed by Carsten Culmsee, Philipps-Universitt Marburg, Germany

Bchler, Germany) at a vibration amplitude of 200 cycles/min

(2015) demonstrated emodin effectively protects NRK-52E cells from LPS-induced injury by downregulating expression of TLR2, NF-B, and inflammatory cytokines